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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE3B
All Species:
31.82
Human Site:
S848
Identified Species:
63.64
UniProt:
Q13370
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13370
NP_000913.2
1112
124333
S848
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Chimpanzee
Pan troglodytes
XP_520783
1141
125048
S863
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Rhesus Macaque
Macaca mulatta
XP_001092891
1117
125088
S848
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Dog
Lupus familis
XP_854529
779
87136
N578
K
A
N
D
V
N
S
N
G
I
E
W
S
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61409
1100
122135
S824
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Rat
Rattus norvegicus
Q63085
1108
123088
S830
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518516
340
38206
A139
A
F
L
V
A
T
N
A
P
Q
Q
N
T
S
S
Chicken
Gallus gallus
NP_001026353
1105
121291
S836
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Frog
Xenopus laevis
NP_001088828
985
108702
L784
K
V
N
D
V
N
G
L
G
I
D
W
S
N
E
Zebra Danio
Brachydanio rerio
XP_691883
1107
124050
S837
A
V
L
Y
N
D
R
S
V
L
E
N
H
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0P7
625
69850
E424
I
E
N
L
D
P
A
E
M
K
R
F
R
Y
L
Sea Urchin
Strong. purpuratus
XP_793920
1558
171759
S1211
A
I
L
Y
N
D
R
S
V
L
E
N
H
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
96.7
60.6
N.A.
81.5
80.6
N.A.
22.4
63.6
59.7
63.2
N.A.
N.A.
N.A.
26.5
28.2
Protein Similarity:
100
58.2
98.2
64.5
N.A.
86.9
86.7
N.A.
26.9
75
70.8
75.5
N.A.
N.A.
N.A.
38.2
41.8
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
20
100
6.6
100
N.A.
N.A.
N.A.
0
93.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
40
100
33.3
100
N.A.
N.A.
N.A.
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
9
0
0
9
0
9
9
0
0
0
0
0
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
67
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
9
0
0
75
0
0
0
17
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
67
67
0
% H
% Ile:
9
9
0
0
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
75
9
0
0
0
9
0
67
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
25
0
67
17
9
9
0
0
0
75
0
17
0
% N
% Pro:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
67
0
0
0
9
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
67
0
0
0
0
17
9
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
67
0
9
17
0
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _